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  1. Research

    A framework for continuous target tracking during MR-guided high intensity focused ultrasound thermal ablations in the abdomen

    During lengthy magnetic resonance-guided high intensity focused ultrasound (MRg-HIFU) thermal ablations in abdominal organs, the therapeutic work-flow is frequently hampered by various types of physiological m...

    Cornel Zachiu, Baudouin Denis de Senneville, Ivan D. Dmitriev, Chrit T. W. Moonen and Mario Ries

    Journal of Therapeutic Ultrasound 2017 5:27

    Published on: 9 October 2017

  2. Review

    Current and emerging brain applications of MR-guided focused ultrasound

    MRI guided focused ultrasound is an emerging technique that uses acoustic energy to noninvasively treat intracranial disorders. At high frequencies, it can be used to raise tissue temperatures and ablate discr...

    Ying Meng, Suganth Suppiah, Karim Mithani, Benjamin Solomon, Michael L. Schwartz and Nir Lipsman

    Journal of Therapeutic Ultrasound 2017 5:26

    Published on: 5 October 2017

  3. Research

    Clinical validation of real-time tissue change monitoring during prostate tissue ablation with high intensity focused ultrasound

    The purpose of these clinical studies was to validate a Tissue Change Monitoring (TCM) algorithm in vivo. TCM is a quantitative tool for the real-time assessment of HIFU dose. TCM provides quantitative analysi...

    Narendra T. Sanghvi, Wo-Hsing Chen, Roy Carlson, Clint Weis, Ralf Seip, Toyoaki Uchida and Michael Marberger

    Journal of Therapeutic Ultrasound 2017 5:24

    Published on: 13 September 2017

  4. Research

    Volumetric magnetic resonance-guided high-intensity focused ultrasound ablation of uterine fibroids through abdominal scars: the impact of a scar patch on therapeutic efficacy and adverse effects

    To retrospectively compare the treatment success, therapeutic efficacy, and adverse effects of magnetic resonance-guided high-intensity focused ultrasound (MRgHIFU) treatment for uterine fibroid patients with ...

    Bilgin Keserci and Nguyen Minh Duc

    Journal of Therapeutic Ultrasound 2017 5:22

    Published on: 17 August 2017

  5. Research

    Effects of HIFU induced cavitation on flooded lung parenchyma

    High intensity focused ultrasound (HIFU) has gained clinical interest as a non-invasive local tumour therapy in many organs. In addition, it has been shown that lung cancer can be targeted by HIFU using One-Lu...

    Frank Wolfram, Georg Dietrich, Carsten Boltze, Klaus Vitold Jenderka and Thomas Günther Lesser

    Journal of Therapeutic Ultrasound 2017 5:21

    Published on: 7 August 2017

  6. Research

    Early health technology assessment of magnetic resonance-guided high intensity focused ultrasound ablation for the treatment of early-stage breast cancer

    Magnetic resonance-guided high intensity focused ultrasound (MR-HIFU) ablation is in development for minimally invasive treatment of breast cancer. Cost-effectiveness has not been assessed yet. An early health...

    Floortje M. Knuttel, Sèvrin E. M. Huijsse, Talitha L. Feenstra, Chrit T. W. Moonen, Maurice A. A. J. van den Bosch, Erik Buskens, Marcel J. W. Greuter and Geertruida H. de Bock

    Journal of Therapeutic Ultrasound 2017 5:23

    Published on: 1 August 2017

  7. Research

    A focused ultrasound treatment system for moving targets (part I): generic system design and in-silico first-stage evaluation

    Focused ultrasound (FUS) is entering clinical routine as a treatment option. Currently, no clinically available FUS treatment system features automated respiratory motion compensation. The required quality sta...

    Michael Schwenke, Jan Strehlow, Daniel Demedts, Sabrina Haase, Diego Barrios Romero, Sven Rothlübbers, Caroline von Dresky, Stephan Zidowitz, Joachim Georgii, Senay Mihcin, Mario Bezzi, Christine Tanner, Giora Sat, Yoav Levy, Jürgen Jenne, Matthias Günther…

    Journal of Therapeutic Ultrasound 2017 5:20

    Published on: 24 July 2017

  8. Research

    Ablation of the sacroiliac joint using MR-guided high intensity focused ultrasound: a preliminary experiment in a swine model

    Dysfunction of the Sacroiliac Joint (SIJ) is one of the key sources of low back pain. For prolonged pain relief, some patients undergo fluoroscopic guided radio-frequency (RF) ablation of SIJ, during which a n...

    Elena A. Kaye, Majid Maybody, Sebastien Monette, Stephen B. Solomon and Amitabh Gulati

    Journal of Therapeutic Ultrasound 2017 5:17

    Published on: 26 June 2017

  9. Research

    Effect of applied energy in renal sympathetic denervation with magnetic resonance guided focused ultrasound in a porcine model

    Past catheter-based and focused ultrasound renal denervation studies have indicated that procedure efficacy is related to the number of ablations performed or the amount of energy used for the ablation. This s...

    Jill Shea, Joshua de Bever, Eugene Kholmovski, Hannah Beal, J. Rock Hadley, Emilee Minalga, Mohamed E. Salama, Nassir F. Marrouche and Allison Payne

    Journal of Therapeutic Ultrasound 2017 5:16

    Published on: 12 June 2017

  10. Research

    Spatially-segmented undersampled MRI temperature reconstruction for transcranial MR-guided focused ultrasound

    Volumetric thermometry with fine spatiotemporal resolution is desirable to monitor MR-guided focused ultrasound (MRgFUS) procedures in the brain, but requires some form of accelerated imaging. Accelerated MR t...

    Pooja Gaur, Beat Werner, Xue Feng, Samuel W. Fielden, Craig H. Meyer and William A. Grissom

    Journal of Therapeutic Ultrasound 2017 5:13

    Published on: 30 May 2017

  11. Research

    Theoretical investigation of transgastric and intraductal approaches for ultrasound-based thermal therapy of the pancreas

    The goal of this study was to theoretically investigate the feasibility of intraductal and transgastric approaches to ultrasound-based thermal therapy of pancreatic tumors, and to evaluate possible treatment s...

    Serena J. Scott, Matthew S. Adams, Vasant Salgaonkar, F. Graham Sommer and Chris J. Diederich

    Journal of Therapeutic Ultrasound 2017 5:10

    Published on: 3 May 2017

  12. Research

    Multi-focal HIFU reduces cavitation in mild-hyperthermia

    Mild-hyperthermia therapy (40–45 °C) with high-intensity focused ultrasound (HIFU) is a technique being considered in a number of different treatments such as thermally activated drug delivery, immune-stimulat...

    Vandiver Chaplin and Charles F. Caskey

    Journal of Therapeutic Ultrasound 2017 5:12

    Published on: 13 April 2017

  13. Research

    A meta-analysis of palliative treatment of pancreatic cancer with high intensity focused ultrasound

    Pancreatic adenocarcinoma is currently the fourth-leading cause of cancer-related death. Up to 60–90% of patients with advanced disease suffer cancer-related pain, severely impacting their quality of life. Cur...

    Susan Dababou, Cristina Marrocchio, Jarrett Rosenberg, Rachelle Bitton, Kim Butts Pauly, Alessandro Napoli, Joo Ha Hwang and Pejman Ghanouni

    Journal of Therapeutic Ultrasound 2017 5:9

    Published on: 1 April 2017

  14. Meeting abstracts

    International Society for Therapeutic Ultrasound Conference 2016

    Brian Fowlkes, Pejman Ghanouni, Narendra Sanghvi, Constantin Coussios, Paul C. Lyon, Michael Gray, Christophoros Mannaris, Marie de Saint Victor, Eleanor Stride, Robin Cleveland, Robert Carlisle, Feng Wu, Mark Middleton, Fergus Gleeson, Jean-Franҫois Aubry, Kim Butts Pauly…

    Journal of Therapeutic Ultrasound 2017 5(Suppl 1):15

    Published on: 17 March 2017

    This article is part of a Supplement: Volume 5 Supplement 1

  15. Research

    Microvessel rupture induced by high-intensity therapeutic ultrasound—a study of parameter sensitivity in a simple in vivo model

    Safety analyses of transcranial therapeutic ultrasound procedures require knowledge of the dependence of the rupture probability and rupture time upon sonication parameters. As previous vessel-rupture studies ...

    Yeonho Kim, Marjan Nabili, Priyanka Acharya, Asis Lopez and Matthew R. Myers

    Journal of Therapeutic Ultrasound 2017 5:5

    Published on: 2 March 2017

  16. Research

    Objective image analysis of real-time three-dimensional intraoperative ultrasound for intrinsic brain tumour surgery

    There is growing evidence that maximal surgical resection of primary intrinsic brain tumours is beneficial, both by improving progression free and overall survival and also by facilitating postoperative chemot...

    Sophie J. Camp, Vasileios Apostolopoulos, Vasileios Raptopoulos, Amrish Mehta, Kevin O’Neill, Mohammed Awad, Babar Vaqas, David Peterson, Federico Roncaroli and Dipankar Nandi

    Journal of Therapeutic Ultrasound 2017 5:2

    Published on: 16 February 2017

  17. Research

    Moderate-to-deep sedation technique, using propofol and ketamine, allowing synchronised breathing for magnetic resonance high-intensity focused ultrasound (MR-HIFU) treatment for uterine fibroids: a pilot study

    Magnetic resonance high-intensity focused ultrasound (MR-HIFU) treatment for uterine fibroids is rapidly gaining popularity as a treatment modality. This procedure is generally uncomfortable, painful, and requ...

    Hermanus H. B. Vaessen, F. M. Knuttel, J. M. M. van Breugel, M. E. Ikink, J. M. Dieleman, M. A. A. J. van den Bosch and J. T. A. Knape

    Journal of Therapeutic Ultrasound 2017 5:8

    Published on: 9 February 2017

  18. Case study

    MRgFUS for desmoid tumors within the thigh: early clinical experiences

    Desmoid tumors are benign but locally aggressive non-malignant tumors derived from fibroblasts. Surgery, chemotherapy, and radiation therapy have been the mainstay of treatment, but recurrence is common and si...

    Matthew D. Bucknor and Viola Rieke

    Journal of Therapeutic Ultrasound 2017 5:4

    Published on: 3 February 2017

  19. Research

    Why we should care about soft tissue interfaces when applying ultrasonic diathermy: an experimental and computer simulation study

    One goal of therapeutic ultrasound is enabling heat generation in tissue. Ultrasound application protocols typically neglect these processes of absorption and backscatter/reflection at the skin/fat, fat/muscle...

    Thaís Pionório Omena, Aldo José Fontes-Pereira, Rejane Medeiros Costa, Ricardo Jorge Simões, Marco Antônio von Krüger and Wagner Coelho de Albuquerque Pereira

    Journal of Therapeutic Ultrasound 2017 5:3

    Published on: 27 January 2017

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