Long-term efficacy of ultrasound-guided high-intensity focused ultrasound treatment of breast fibroadenoma

Table 2 Treatment characteristics at each HIFU session

	Group 1 (n = 19)	Group 2 (n = 7)
	1^st HIFU	1^st HIFU	2^nd HIFU
Treated volume (mL), median (range)	0.78 (0.35–2.24)^a	2.66 (0.52–3.01)	1.34 (0.65–2.24)
Treated volume (%), mean ± SD	56.96 ± 25.05	36.02 ± 7.92^b	58.50 ± 22.34
Total delivered energy (kJ), median (range)	10.1 (4.4–25.4)^c	27.7 (7.4–39.6)	16.5 (12.8–31.4)
Energy per treated volume (kJ/mL), median, range	12.4 (6.7–14.3)	13.0 (10.4–14.2)	13.9 (7.1–14.8)
Treatment duration (min) mean ± SD	60.6 ± 22.8^d	105.1 ± 38.8	66.3 ± 15.7
Number of treated sites, median (range)	58 (29–149)^e	179 (38–221)	95 (40–153)
Hyperechoic marks (%), median (range)	15 (0–31)	10 (0–29)	7 (0–50)

^a p < 0.05 compared with group 2 at the 1^st HIFU and group 2 at the 2^nd HIFU, Mann-Whitney U test, ^b p < 0.05 compared with group 1 and group 2 at the 2^nd HIFU, Student’s t-test, ^c p < 0.01 compared with group 2 at the 1^st HIFU and group 2 at the 2^nd HIFU, Mann-Whitney U test, ^d p < 0.001 compared with group 2 at the 1^st HIFU, Student’s t-test, ^e p < 0.05 compared with group 2 at the 1^st HIFU, Mann-Whitney U test

ISSN: 2050-5736