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Table 3 Results for treatment impact given as the baseline compared to end results for the final exam before sacrifice (mean ± standard deviation)

From: Multiple ultrasound cavitation-enabled treatments for myocardial reduction

 

Echo wall (mm)

Ejection Fraction

Echo Strain (%)

Displace. (mm)

Histo wall

Fibrosis

Group

Baseline

End

Baseline

End

Baseline

End

Baseline

End

mm

Area %

A

1.7 ± 0.1

1.7 ± 0.1

80 ± 3

77 ± 1

51 ± 7

46 ± 4

0.88 ± 0.13

0.76 ± 0.08

2.3 ± 0.4

0

B

1.7 ± 0.1

2.0 ± 0.1**

79 ± 1

75 ± 2**

45 ± 8

30 ± 5**

0.92 ± 0.06

0.76 ± 0.08*

2.4 ± 0.2

40 ± 10a

C

1.8 ± 0.1

1.9 ± 0.2*

80 ± 4

77 ± 5

46 ± 5

36 ± 8*

0.87 ± 0.08

0.84 ± 0.11

2.4 ± 0.4

29 ± 16a

D

1.9 ± 0.2

1.5 ± 0.2**

79 ± 3

65 ± 6**

45 ± 7

25 ± 7**

0.88 ± 0.08

0.54 ± 0.11**

1.8 ± 0.3a

49 ± 8a

  1. Significant differences versus baseline denoted by * for p < 0.05 or ** for p < 0.01. Significant difference versus sham (A) denoted by a. In addition, the fibrosis was higher in D than in C (p < 0.05), but there was no significant differences for the other comparisons (B versus C, and B versus D)