Table 1 Duration of treatment steps and probability of events for clinically applied MR-HIFU breast cancer treatments as predicted by experts compared to data from the MR-HIFU feasibility study

Positioning

Time patient verification

min

15

10

25

11.5

Time verification reachability

min

15

7

20

14.5

Time target definition

min

8

5

15

n/a

Chance of repositioning

-

0.30

0.10

0.75

n/a

Test

Time to place navigator

min

2

1

10

1

Time MRI scan

min

2.5

1

15

2.5

Time for treatment planning

min

2

1

5

n/a

Time to fill LUT

min

2.75

0

5

n/a

Test sonication and check focal point

min

3

1

5

4

Chance of adjustment focal point per coronal plane

-

0.55

0.20

0.90

n/a

Therapeutic

Time therapeutic phase

min

0.50

0.25

0.75

n/a

Cooling time after each sonication

min

3.5

1

10

n/a

Chance of abortion per coronal plane

-

0,10

0,05

0,20

n/a

Chance of resonication per coronal plane

-

0.20

0.10

0.30

n/a

Post-treatment

Time clinical ward

min

240

120

300

n/a

Chance of complications

-

0.015

0.01

0.03

n/a