Table 5 (abstract 70). Extracted parameters for each compound (Dotarem, Gadovist, MultiHance and AGuIX). Notably, the apparent dH estimated from the Stokes-Einstein equation is in agreement with DLS measurements, and both DFree and ADC values decrease when molecular size increases. The tortuosities are consistent for all compounds and in agreement with literature
From: International Society for Therapeutic Ultrasound Conference 2016
Number of Rats | r1 at 7T (s−1·mM −1) | DFree (10−11 m2·s−1) | ADC (10−11 m2·s−1) | Stokes Einstein dH (nm) | DLS dH (nm) | λ | |
|---|---|---|---|---|---|---|---|
Dotarem | 3 | 4.7 | 45 | 16 | 1.5 | 1.4 | 1.7 |
Gadovist | 3 | 5.5 | 39 | 15 | 1.7 | 1.8 | 1.6 |
MultiHance | 3 | 7.3 | 28 | 11 | 2.3 | 2.3 | 1.6 |
AGuIX | 2 | 8.0 | 11 | 6 | 5.8 | 3.5 | 1.5 |