Fig. 87 (abstract O68).

Scatter plot of normalized Dox concentration (the outcome) versus cavitation noise level (a) and cavitation persistence (b). The outcomes tend to increase with both the persistence and the noise level. The data from control group (squares), outcomes from the simultaneous treatment group (circles) as well as from sequential treatment group (triangles) are shown. The result lines from generalized estimating equation (GEE) model of cavitation noise level (a) and cavitation persistence (b) are also plotted for the simultaneous pHIFU treatment and Dox administration (dash line) and the Dox administration after pHIFU treatment (solid line)