Fig. 158 (abstract P15).

a MR-guided histotripsy experimental setup. The setup consisted of a polyacrylamide gel placed in a 3D-printed holder in a degassed water bath (white tank). This entire setup was placed over the HIFU transducer. b typical boiling histotripsy lesion produced using the clinical MR-HIFU system with 600 W, 1 Hz PRF and 15000 cycles/pulse. The lesion has a characteristic tadpole-looking shape. c maximum temperature value in each ROI was plotted as function of time for all different PRFs. An exponential temperature increase, but the time constants and decays are different between 0.5 Hz (cyan curve) and 5 Hz (dark blue curve) PRF. d Lesion volumes were somewhat reproducible and showed some consistency between the two repetitions. Lesion volumes substantially increased between 10000 cycles/pulse and 20000 cycles/pulse