Table 2 Potential large animal application with DUS-targeted gene delivery
Disease entity | DUS frequency/trigging | Specific gene | Specific application |
|---|---|---|---|
Diabetes | 1:4 | DNA-planned | Beta cell regeneration |
Limb ischemia | 1:4 | DNA-planned VGE | Angiogenesis |
Tumor | Â | DNA | Tumor suppression |
Tumor | 1:10 | ShRNA | Anti-angiogenesis |