Fig. 6
Trajectory drawing and application to hemispheric and global permeabilization. a (resp. d and f) Trajectories which were designed in the control software for hemispheric BBB disruption in rats (resp. global BBB permeabilization in rats and hemispheric BBB disruption in mice). c (resp. g) Axial T1-weighted image obtained after Gd chelate injection, showing contrast enhancement only in the hemisphere which has been disrupted in rat (resp. mice). b The corresponding T1-weighted image obtained in the same rat in horizontal orientation. e T1-weighted image obtained in horizontal orientation for the rat with global BBB permeabilization