Cost comparison between uterine-sparing fibroid treatments one year following treatment

Table 6 Mean annual costs for treatment groups and comparison group, showing calculation of fibroid-related costs (95% confidence intervals)

	MRgFUS		UAE		Myomectomy
	Treated	Matched comparison	Treated	Matched comparison	Treated	Matched comparison
	(n = 14)	(n = 70)	(n = 4,092)	(n = 4,092)	(n = 10,320)	(n = 10,320)
Unadjusted costs
Operative costs (pre-, peri- and post-operative costs for treated, year after index date in comparison group)	$17,719	$4,066	$18,638	$7,798	$16,879	$8,973
	($10,068, $25,370)	($2,376, $5,755)	($17,943, $19,332)	($7,268, $8,328)	($16,592, $17,167)	($8,664, $9,283)
Uterine fibroid related costs in year after surgery (operative costs treated minus comparison group)	$13,653		$10,839		$7,906
	($4,944, $22,362)		($10,358, $11,320)		($7,574, $8,328)
Regression adjusted costs ^*
Operative costs (pre-, peri- and post-operative costs for treated, year after index date in comparison group)	$19,763	$5,149	$25,019	$8,712	$20,407	$8,512
	($10,425, $38,694)	($3,883, $6,892)	($23,738, $26,376)	($8,290, $9,154)	($19,483, $21,381)	($8,092, $8,952)
Uterine fibroid related costs in year after surgery (operative costs treated minus comparison group)	$14,614		$16,307		$11,895
	($7,469, $21,759)		($12,949, $19,665)		($7,996, $15,794)

^*Adjusted costs employed regression models (generalized linear model with gamma distribution and logarithmic link) to control for baseline differences between women receiving each treatment. The regression included the following control variables, all measured on the index date or during the 1 year baseline period: age, region, type of health plan, year of procedure, whether the patient was an employee or dependent, whether or not the employee was active full-time, whether the employee was salaried, demographics characteristics of the ZIP Code where the patient lived, indicators for any outpatient prescription drug fills of hormone therapies and NSAIDs, the Deyo Charlson Comorbidity Index, number of psychiatric diagnostic groupings, indicators for comorbidities, and indicators for any hospital stays and any emergency department visits during the baseline year. Demographics of the ZIP code included quintile of zip code median family income, quintile of percent black and quintile of percent with a college degree.

ISSN: 2050-5736