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Table 2 Treatment characteristics

From: First experience with MR-guided focused ultrasound in the treatment of Parkinson's disease

  Patient no. Sonication target and side Final temperature (°C) Global symptom relief 3 months (%) Pre-FUS UPDRS I/II/III/IV (max. 16/52/56/23, total 147) 3 months post-FUS UPDRS I/II/III/IV (max. 16/52/56/23, total 147) Pre-FUS MMST (max. 30) 3 months post-FUS MMST (max. 30) Pre-FUS HADS (max. 42) 3 months post-FUS HADS (max. 42)
Group 1 1 PTT right 52 0 0/2/3/6 2/11/5/7 29 30 17 20
Total 11 Total 25
2 PTT right 52 30 0/14/17/3 0/10/17/2 30 30 9 4
Total 34 Total 29
3 PTT right 57 40 0/18/29/4 1/20/24/2 29 29 12 18
Total 51 Total 47
4 PTT right 59 20 0/18/26/5 0/12/20/1 27 27 13 9
Total 49 Total 33
Group 2 5 PTT right 59 50 0/5/18/5 0/1/7/0 30 30 5 9
Total 28 Total 8
6 PTT left 57 55 1/10/15/5 0/6/6/0 29 30 20 19
Total 31 Total 12
7 PTT left 57 80 4/21/20/6 1/12/2/4 30 30 13 14
Total 51 Total 19
8 PTT right 58 5 0/10/22/5 0/9/15/0 29 30 11 9
Total 37 Total 24
9 PTT left 57 50 4/17/19/10 1/5/2/4 30 29 34 26
Total 50 Total 12
10 PTT right 56 50 3/9/20/7 3/6/4/0 29 30 14 18
Total 39 Total 13
11 PTT right 56 80 0/19/29/4 2/9/13/0 30 29 12 3
Total 53 Total 24
12 PTT right 56 70 0/5/14/6 1/3/8/0 29 30 9 10
Total 25 Total 12
13 PTT left 54 70 3/22/11/8 3/4/9/0 26 28 14 10
Total 44 Total 16
Mean   - 56.2 - - - 29 29.4 14.1 13
  1. The treatment characteristics include the target and side and the mean and maximum temperatures achieved during treatment. The subjective 3-month follow-up global symptom relief, as well as the pre- and post-FUS UPDRS scores shown here, are also displayed on Figure 4. The pre- and post-operative Mini Mental State Test (MMST) scores as well as Hospital Anxiety and Depression Scores (HADS) on the last four rows show no cognition losses and no emotional worsening for both groups of patients.