Figure 5
From: Focused ultrasound-mediated drug delivery to pancreatic cancer in a mouse model
Images of mouse, maximum temperature projection in time, MRgFUS trajectory, temperature response for voxels, and time curve. (A) Axial image of a mouse on the MRgHIFU device. The transducer and agar holder are shown. (B) Coronal image through the tumor with region of interest defined. (C) Maximum temperature projection in time within region of interest. White rectangle indicates the grid trajectory boundaries. (D) MRgFUS trajectory with plotted voxel locations indicated. One-millimeter spacing between all points. (E) Temperature response as a function of time for voxels indicated in (D). (F) Time curve of the mean temperature rise in the treatment plane for all voxels >5°C. Total MRgFUS time was 350 s at a pressure of 3.4 MPa.