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Fig. 1 (abstract O30). | Journal of Therapeutic Ultrasound

Fig. 1 (abstract O30).

From: Abstracts from the International Society for Therapeutic Ultrasound Conference 2017

Fig. 1 (abstract O30).

In vivo brain drug delivery distributions using (a, b) rapid short­pulse (RaSP) or (c, d) conventional sequences. The (a, c) left hippocampus of the mouse brain was sonicated in vivo after systemic delivery of fluorescently­labelled 3­kDa dextran and microbubbles. The (b, d) right hippocampus was not treated and acted as our control (b, d). Sonication using (a) a RaSP sequence delivered a greater dose of dextran to the brain parenchyma with less delivery to arteries than (c) conventional sequences

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