Fig. 1 (abstract P61).

(A) Upper: The 3­D cell morphology reconstruction before and after ultrasound sonication. When DNA­loaded MBs were destructed into fragments, a pore onto cell membrane was generated and the fragments were spread around the site of pore; lower: another case, the debris was co­localized with the cell membrane after ultrasound sonication. (blue: cyan fluorescence protein labeled cell membrane; red: Rhodamine­labeled DNA­loaded MBs) (B) Time­lapse images confirmed the gene was transported to cell nuclei from DNA­loaded MBs after ultrasound sonicaton. (red: Rhodamine­labeled DNA­loaded MBs; green: YFP­labeled cell membrane; blue: DAPIdye labeled cell nuclei)