Fig. 1 (abstract P5).From: Abstracts from the International Society for Therapeutic Ultrasound Conference 2017(A) After microbubbleÂfacilitated FUS treatment at left hemisphere, EB entered into the brain, indicating the BBB is opened. Some hemorrhage was observed. One unit of scale is 1 mm. (B) VLP fused with mcherry fluorescent protein entered into the left hemisphere after BBB opening induced by microbubbleÂfacilitated FUS.VLP was shown as red. Nuclei were stained by DAPI. (C) Compared with saline injection or VLP injection without FUS, more VLPs were coÂlocalized with NeuN after BBB opening, indicated its entry into the neuron cells. VLP was presented as green, NeuN was as red and nuclei was as blueBack to article page