Table 1 Inadequate Biological and Haematological Indices

International Normalised Ratio

> 1.5 times the institution’s upper normal limit (unless anti-coagulated)

Absolute neutrophil count

<1500/mm³ (or <1.5 (10⁹/L))

Platelet count

< 60,000 /mm³ (or <60 (10⁹/L))

Haemoglobin

< 9.0 g/dL

Serum creatinine

Calculated creatinine clearance (CrCl)

≥ 2.5 mg/dL (or ≥221 μmol/L)

≤ 25.0 mL/min

Serum bilirubin

> 3.0 mg/dL (or >51 μmol/L)

Serum albumin

< 2.8 g/dL (or <28g/L)