Effect of applied energy in renal sympathetic denervation with magnetic resonance guided focused ultrasound in a porcine model

Table 3 Summary of study parameters. Time to Evaluation (TTE) was either 9 days (9d) or 6 months (6 m)

Animal ID	TTE	Acoustic Power (W)	Mean propagation path length, z (cm)	Derated Intensity, I _D (kW/cm²)	Medulla norepinephrine (ng/mL/g)			Spinous process enhancement (mm)
Animal ID	TTE	Acoustic Power (W)	Mean propagation path length, z (cm)	Derated Intensity, I _D (kW/cm²)	Left	Right	Ratio (R/L)	Spinous process enhancement (mm)
11	9d	80	8.9	0.40	2322	1322	0.57	0
2	9d	80	8.6	0.41	1131	1480	1.31	0
9	6 m	80	7.5	0.62	1655	2440	1.47	0
12	9d	80	7.3	0.65	2402	1187	0.49	20
20	9d	80	7.2	0.67	1658	3239	1.95	0
18	9d	80	7.1	0.70	2248	1334	0.59	0
5	6 m	80	7.1	0.74	591	1241	2.10	0
17	9d	80	6.5	0.81	810	771	0.95	21
8	9d	200	9.5	0.90	992	1139	1.15	19
7	6 m	140	7.8	1.00	3048	2907	0.95	0
14	9d	140	7.7	1.04	484	789	1.63	18
1	9d	140	7.5	1.10	899	2572	2.86	9
21	9d	140	7.5	1.11	855	892	1.04	20
3	9d	200	8.0	1.19	992	2246	2.26	7
19	9d	140	7.0	1.31	4478	1350	0.30	28
4	6 m	140	6.9	1.33	229	29	0.12	19
15	9d	200	8.0	1.38	861	953	1.11	38
13	9d	200	7.7	1.49	1880	1216	0.65	20
6	6 m	200	7.3	1.49	646	295	0.46	0
16	9d	140	6.4	1.54	539	385	0.71	17
23	9d	140	6.3	1.54	1027	197	0.19	11
24	9d	200	7.6	1.59	1339	837	0.63	22
10	6 m	200	7.3	1.70	1065	1457	1.37	0
22	9d	200	7.2	1.78	653	311	0.48	27

Spinous process enhancement measures the maximum length of any hyper intensity present around the right spinous process after the post-contrast 3D T1w VIBE images. The solid line separator indicates the animal treated with a low or high derated acoustic intensity (1.2 kW/cm² threshold)

ISSN: 2050-5736