Moderate-to-deep sedation technique, using propofol and ketamine, allowing synchronised breathing for magnetic resonance high-intensity focused ultrasound (MR-HIFU) treatment for uterine fibroids: a pilot study

Table 2 Sedation-related events during MR-HIFU treatment (N = 20)

	Heart rate Min max mean	SpO₂ Min max mean	Capnography Min max mean	Resp. rate Min max mean	Mean NIBP Min max mean	OAA/S score Min max mean
1 min	50 112 79.9	94 100 98	4.5 6.0 5.2	10 20 14	79 112 98	5 5 5.0
30 min	54 102 73.2	96 100 98	4.6 5.8 5.4	9 18 14	71 110 86	3 4 3.8
60 min	56 100 72.4	95 99 97	4.5 6.2 5.5	9 20 14	62 105 79	2 5 3.1
90 min	50 90 71.0	94 99 97	4.5 6.2 5.7	8 20 13	62 90 74	2 4 2.6
120 min	54 92 71.7	94 99 97	4.9 6.3 5.8	8 24 15	64 94 79	2 4 2.5
150 min	50 96 71.7	94 100 97	5.0 6.2 5.7	8 24 15	62 102 81	2 3 2.5
180 min	48 92 71.4	94 100 97	4.4 6.1 5.6	8 25 15	68 95 80	2 3 2.6
210 min	50 90 72.0	95 100 97	4.9 6.1 5.5	8 24 14	68 94 84	2 4 2.8
240 min	54 90 72.0	96 100 98	5.0 5.9 5.5	9 24 15	67 99 85	2 4 3.1
270 min	54 88 77.2	96 100 98	5.3 5.9 5.5	12 18 14	80 101 87	3 5 4.0

Min minutes after start patient records registration, HR heart rate/minute, SpO ₂ saturation of peripheral oxygen in %, Capnography capnography in vol %, Resp. rate respiratory rate/minute, Mean NIBP mean non-invasive blood pressure in mmHG, OAA/S observer’s assessment of alertness/sedation

ISSN: 2050-5736