Table 2 Parameter values along with bibliographic references of the curves shown in Fig. 3. “Time to offset” is the time for the tumor to come back to the initial value. Curves n. 5 and 6 are calculated with 1-h delay between the end of RT and the beginning of HT. Curves 7 and 8 are calculated with 2-h delay between the end of RT and the beginning of HT
Number | Title | α (Gy−1) | β (Gy−2) | Minimum survival value | Time to offset | Reference |
|---|---|---|---|---|---|---|
1 | Only RX (unrealistic) | 5.4 × 10−2 | 4.2 × 10−2 | 3.61 × 10−4 | 2.29 years | [108] |
2 | Yu 2 Gy × 30–CSCs | 1 × 10−2 1.25 × 10−1 | 1.77 × 10−7 2.8 × 10−2 | 1.66 × 10−2 | 210 days | [122] |
3 | Yu–Extrapolated | 1 × 10−2 1.25 × 10−1 | 1.77 × 10−7 2.8 × 10−2 | – | – | Extrapolation of the previous SF |
4 | Powathil 2 Gy × 30 | 2.7 × 10−2 | 2.7 × 10−3 | 1.89 × 10−1 | 226 days | [20] |
5 | RX + HT 3 Gy × 12–1 h | 3.36 × 10−1 | 8.7 × 10−2 | 2.897 × 10−8 | 4.61 years | [108] |
6 | RX + HT 4.7 Gy × 6–1 h | 3.36 × 10−1 | 8.7 × 10−2 | 4.986 × 10−8 | 4.48 years | [108] |
7 | RX + HT 3 Gy × 12–2 h | 3.36 × 10−1 | 8.7 × 10−2 | 3.286 × 10−7 | 4.02 years | [108] |
8 | RX + HT 4.7 Gy × 6–2 h | 3.36 × 10−1 | 8.7 × 10−2 | 4.986 × 10−7 | 3.91 years | [108] |