Table 1 MR imaging sequences and parameters

Gem

TE = 6–15 ms

Gradient echo sequence for PRF-shift thermometry.

TR = 30 ms

All monitoring was conducted in a single

Angle = 25

slice in the MRI axial plane, parallel to the direction

Mat = 96×96

of acoustic propagation. 1–2 dummy

FOV = 60×60 mm

scans were used to suppress steady-state artifacts.

Fsems

TE = 37 ms

TR = 3000 ms

Fast spin echo sequence for T ₂-weighted anatomical

ETL = 8

imaging. Enables tumor localization and visualization

ESP = 9 ms

of the surrounding environment.

Angle = 20

Mgems

TE = 2 ms

ΔTE = 3 ms

TR = 30 ms

Multi-echo gradient echo scan for water/fat separation

Angle = 25

in post-treatment analysis.

Mat = 96×96

FOV = 60×60 mm

Gems_meg

TE = 7.6 ms

Modified gradient echo sequence for ARFI. G_dur

TR = 71 ms

represents the duration a single lobe of the biopolar

G_amp = 10 G/cm

MEG. The direction of motion encoding was

G_dur = 4 ms

controlled within the scanner interface based on

FUS = 1.1 MHz

the slice orientation.