Table 1 Overview of the number of sonications performed to create a lesion per experiment performed either under procedural sedation and analgesia (PSA) or general anesthesia (GA), of the non-perfused volume (NPV) obtained from these sonications, the mean NPV created per sonication, the non-viable volume as observed by nicotinaminde adenine dinucleotide (NADH) staining for the entire cluster, and the mean non-viable volume per sonication
From: Procedural sedation and analgesia for respiratory-gated MR-HIFU in the liver: a feasibility study
Experiment | #sonications | NPV (mL) | NPV/sonication (mL) | |||
| Â | PSA | GA | PSA | GA | PSA | GA |
1 | 7 | 10 | 0.70 | 0.70 | 0.10 | 0.070 |
2 | 8 | 9 | 1.16 | 0.51 | 0.15 | 0.057 |
3 | 7 | 7 | 1.13 | 1.29 | 0.16 | 0.18 |
4 | 7 | 7 | 1.50 | 0.55 | 0.21 | 0.079 |
5 | 7 | 7 | 1.31 | 0.56 | 0.19 | 0.080 |
6 | 7 | 7 | – | – | – | – |
7 | 7 | 7 | 0.48 | 0.94 | 0.069 | 0.13 |
8 | 7 | 7 | 1.30 | 0.96 | 0.19 | 0.14 |
Experiment | NADH (mL) | NADH/sonication (mL) | ||||
| Â | PSA | GA | PSA | GA | ||
1 | 0.89 | 0.46 | 0.13 | 0.046 | ||
2 | 0.95 | 0.19 | 0.12 | 0.021 | ||
3 | 0.13 | 0.46 | 0.019 | 0.066 | ||
4 | 1.01 | 0.05 | 0.14 | 0.0071 | ||
5 | 1.55 | 0.47 | 0.22 | 0.067 | ||
6 | – | – | – | – | ||
7 | 0.41 | 0.74 | 0.056 | 0.11 | ||
8 | 0.92 | 0.89 | 0.13 | 0.13 | ||