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Fig. 3 | Journal of Therapeutic Ultrasound

Fig. 3

From: Utilization of diagnostic ultrasound and intravenous lipid-encapsulated perfluorocarbons in non-invasive targeted cardiovascular therapeutics

Fig. 3

Demonstration of reformation of beta cells (pink-stained cells) following DUS-guided high MI-targeted delivery of plasmid DNA encoding for cyclin D2/CDK4/GLP1 in high doses (panel d). Panel a demonstrates a normal baboon pancreas. Note the numerous pink-stained cells that are now present. Panel b is UTMD control. Panel c is UTMD with low dose gene therapy. Bottom panel e demonstrates the fraction of beta cells present + US-guided therapies

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