Focal therapy using magnetic resonance image-guided focused ultrasound in patients with localized prostate cancer

Table 1 MRI parameters

Pulse sequence name	Axial T1 FSE	Axial/sag/coronal T2 FRFSE			Axial DWI echo planar imaging (EPI)			Axial DCE GRE/FSPGR	Pre-DCE T1 maps
Plane(s) of acquisition	Obl/Axial	oAx	oSag	oCor	oAx			Ax	Ax	Ax	Ax
TR (msec)	750	2520	3050	2830	4275			2.5	2.5	2.5	2.5
TE (msec)	7.0	117	102	102	80			0.8	0.8	0.8	0.8
Flip angle	90	90	90	90	90			12	15	10	5
Matrix (cm)	256/192	320/256	320/256	320/256	128/128			160/160	160/160	160/160	160/160
Field of view (cm)	38/30	22/22	18/18	18/18	38/38			22/22	22/22	22/22	22/22
Slice thickness and slice gap (mm)	5.0/1.0	3.0/0.5	3.0/0.5	3.0/0.5	3.0/0.5			5.0/0.0	5.0/0.0	5.0/0.0	5.0/0.0
Number of signal averages	3	4	3	3	2	3	3	1.1	2.0	2.0	2.0
Parallel imaging factor					TETRA/asset
Presence of fat suppression	None	None	None	None	Yes			None	None	None	None
3 B values (s/mm²)	None	None	None	None	100	800	1400	None	None	None	None

Vendor: GE 3T HDxt 16.0. Field strength 3 T. Type of coil (number of channels): HD TORSO ARRAY 8 CH. No endorectal coil. For DCE: concentration of gadolinium (use 0.1 mmol/kg) MultiHance (gadobenate dimeglumine); rate of power injection 3 ml/s/volume based on weight of patient; volume of saline flush 3 ml/s/20 ml saline flush; injection and scan delay: imaging begins/acquired immediately. After 22 s of imaging, gadolinium is injected (22-s contrast injection scan delay); time per phase 8 s per phase/total scan time 04:33; number of phases 35
EPI echo planar imaging, FRFSE fast-relaxation fast spin echo, FSE fast spin echo, GRE gradient echo, DCE dynamic contrast exam, FSPGR fast spoiled gradient echo, DWI diffusion-weighted imaging