Fig. 1
From: Focused ultrasound-aided immunomodulation in glioblastoma multiforme: a therapeutic concept
Synopsis. The key established mechanisms hampered in GBM and the key immune-modulating effects of HIFU are presented. A theoretical action-reaction scheme is presented, connecting certain known GBM-evasion mechanisms with the FUS-induced counter response. Note that a single FUS-induced effect may influence a multitude of immunosuppressive mechanisms and vice versa. Refer to text