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Fig. 3 | Journal of Therapeutic Ultrasound

Fig. 3

From: Magnetic resonance-guided motorized transcranial ultrasound system for blood-brain barrier permeabilization along arbitrary trajectories in rodents

Fig. 3

Overview of the BBB permeabilization experiment. The different steps are summed up in the first row. The rodents are shaved and installed in the bed under anesthesia, and a catheter is set in the caudal vein. It is then inserted in the magnet where reference scans (second row, a and b) and positioning procedure are performed using ARFI images and the motors. The BBB permeabilization procedure is performed followed by MR contrast agent injection and post-permeabilization MR image acquisition (c). MB = microbubbles. The red arrow indicates the BBB permeabilization visible by a contrast enhancement on the T1-weighted image (c)

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