Fig. 3From: Magnetic resonance-guided motorized transcranial ultrasound system for blood-brain barrier permeabilization along arbitrary trajectories in rodentsOverview of the BBB permeabilization experiment. The different steps are summed up in the first row. The rodents are shaved and installed in the bed under anesthesia, and a catheter is set in the caudal vein. It is then inserted in the magnet where reference scans (second row, a and b) and positioning procedure are performed using ARFI images and the motors. The BBB permeabilization procedure is performed followed by MR contrast agent injection and post-permeabilization MR image acquisition (c). MB = microbubbles. The red arrow indicates the BBB permeabilization visible by a contrast enhancement on the T1-weighted image (c)Back to article page