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Table 1 Bloom–Richardson classification of tumors in sham and treated groups

From: Evaluation of fractionated and repeated sonodynamic therapy by using dual frequency for murine model of breast adenocarcinoma

Group

Tumor tubule formation

Number of mitoses/10-high-power fields

Nuclear grade

Total score

Bloom–Richardson grade

Grade

Sham

2

3

2

7

Moderately differentiated (BR intermediate grade)

2

Dual-frequency sonication + Hp

1

2

3

6

Moderately differentiated (BR intermediate grade)

2

Dual-frequency sonication + Hp (two repetitions)

1

2

3

6

Moderately differentiated (BR intermediate grade)

2

Dual-frequency sonication + Hp (three repetitions)

1

2

3

6

Moderately differentiated (BR intermediate grade)

2

Dual-frequency sonication + Hp (four repetitions)

1

1

2

4

Well differentiated (BR low grade)

1

Dual-frequency sonication + Hp (four fractions)

1

1

2

4

Well differentiated (BR low grade)

1