Prediction and suppression of HIFU-induced vessel rupture using passive cavitation detection in an ex vivo model

Table 1 Exposure conditions and times to rupture for all vessels sonicated in the rupture prediction experiments

Trial	AWG output voltage (mVpp)	Measured acoustic power (W)	Computed focal intensity I_SPTP(W/cm²)	Computed peak negative pressure (MPa)	Time to rupture (s)
1	250	20.28	15,690	10.92	29
2	250	20.28	15,690	10.92	133
3	275	26.45	20,570	11.83	27
4	275	26.45	20,570	11.83	25
5	275	26.45	20,570	11.83	NR
6	275	26.45	20,570	11.83	NR
7	280	26.96	20,940	11.90	NR
8	285	27.53	21,350	11.97	14
9	285	27.53	21,350	11.97	32
10	300	28.42	21,980	12.09	55
11	300	28.42	21,980	12.09	41
12	300	28.42	21,980	12.09	60
13	300	28.42	21,980	12.09	19
14	300	28.42	21,980	12.09	133
15	300	28.42	21,980	12.09	35
16	325	32.06	24,430	12.52	55
17	325	32.06	24,430	12.52	67
18	325	32.06	24,430	12.52	42

In trials 5–7, NR indicates that no rupture occurred. AWG arbitrary waveform generator.

ISSN: 2050-5736