Figure 1

Optical and ultrasound visualization of different types of lesions in 6% BSA polyacrylamide TMM phantoms. The 'cigar’-shaped lesions (a) are typically created through thermal mechanisms only. The 'tadpole’-shaped (b) and 'egg’-shaped (c) lesions on the other hand are created by acoustic cavitation activity in the prefocal region (the FUS ultrasound transducer was on the right side). This interpretation is supported by the fact that the cavitation-based lesions are more visible by ultrasound due to the enhanced echogenicity of these regions (reprinted with permission from [11]).