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Table 3 Patient and fibroid characteristics evaluated using univariate analysis

From: Clinical predictors of successful magnetic resonance-guided focused ultrasound (MRgFUS) for uterine leiomyoma

Characteristic HR (95% CI)a Univariate Cox models p value
Age at treatment (years) 0.63 (0.46 to 0.86) 0.003
BMI (kg/m2) 0.90 (0.64 to 1.28) 0.57
Ever pregnant (yes vs. no) 0.72 (0.34 to 1.52) 0.39
Ever live birth (yes vs. no) 0.80 (0.38 to 1.71) 0.57
Smoking history (yes vs. no) 0.45 (0.18 to 1.12) 0.09
Symptom severity score (SSS)b 1.18 (0.87 to 1.59) 0.29
Duration of dominant symptom (months) 0.95 (0.79 to 1.15) 0.60
Pelvic pressure (yes vs. no) 0.42 (0.20 to 0.89) 0.023
Back pain (yes vs. no) 0.53 (0.13 to 2.26) 0.39
Presenting symptoms   0.94
 Bleeding only Referent  
 Bulk only 0.78 (0.27 to 2.25)  
 Bleeding and bulk 0.77 (0.30 to 1.96)  
 Pain (with or without bleeding or bulk) 0.76 (0.23 to 2.51)  
Past medical history   
Anemia (yes vs. no) 0.50 (0.22 to 1.13) 0.10
Hypertension (yes vs. no) 1.95 (0.46 to 8.36) 0.37
History of asthma (yes vs. no) c 0.10
History of migraines (yes vs. no) 2.00 (0.92 to 4.35) 0.08
History of pelvic or uterine surgery (yes vs. no) 2.29 (1.03 to 5.08) 0.042
Thyroid disease (yes vs. no) 1.56 (0.63 to 3.84) 0.34
Prior GnRH agonist therapy 3.92 (1.33 to 11.51) 0.013
Prior usage of oral contraceptives (yes vs. no) 2.02 (0.84 to 4.85) 0.11
Prior iron supplementation (yes vs. no) 0.63 (0.26 to 1.56) 0.32
Prior thyroid hormone therapy (yes vs. no) 1.56 (0.63 to 3.84) 0.34
Fibroid characteristic   
Prior treatment (yes vs. no) 1.58 (0.71 to 3.51) 0.26
Fibroid type   0.52
 Submucosal 1.36 (0.51 to 3.65)  
 Subserosal 0.4 (0.09 to 1.72)  
 Transmural 0.78 (0.18 to 3.35)
 Intramural Referent
Number of fibroids   0.029
 1 Referent  
 2 to 3 0.65 (0.28 to 1.52)  
 >3 0.19 (0.06 to 0.66)  
Volume of largest fibroid (cm3) 0.80 (0.61 to 1.06) 0.11
Total fibroid volume (cm3) 0.70 (0.52 to 0.95) 0.022
T2 signal intensity   
“Dark with min. heterogeneity” vs. all others 0.73 (0.35 to 153) 0.40
All dark vs. “isointense” and “bright” 0.85 (0.29 to 2.45) 0.76