Figure 1
From: Focused ultrasound-mediated drug delivery to pancreatic cancer in a mouse model
A nanoparticle size distribution for 5% PEG-PDLA/1% PFCE formulation. Fifty-nanometer particles are residual micelles; two-hundred sixty-two-nanometer particles are nanodroplets. Nanodroplet size may be decreased by increasing sonication pressure during emulsification. Micelle fraction can be decreased by decreasing copolymer concentration and/or increasing PFCE concentration [46]. PTX loading slightly increases nanodroplet sizes (e.g., from 260 to 280 nm).