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  1. Meeting abstracts

    International Society for Therapeutic Ultrasound Conference 2016

    Brian Fowlkes, Pejman Ghanouni, Narendra Sanghvi, Constantin Coussios, Paul C. Lyon, Michael Gray, Christophoros Mannaris, Marie de Saint Victor, Eleanor Stride, Robin Cleveland, Robert Carlisle, Feng Wu, Mark Middleton, Fergus Gleeson, Jean-Franҫois Aubry, Kim Butts Pauly…

    Journal of Therapeutic Ultrasound 2017 5(Suppl 1):15

    Published on: 17 March 2017

    This article is part of a Supplement: Volume 5 Supplement 1

  2. Research

    Microvessel rupture induced by high-intensity therapeutic ultrasound—a study of parameter sensitivity in a simple in vivo model

    Safety analyses of transcranial therapeutic ultrasound procedures require knowledge of the dependence of the rupture probability and rupture time upon sonication parameters. As previous vessel-rupture studies ...

    Yeonho Kim, Marjan Nabili, Priyanka Acharya, Asis Lopez and Matthew R. Myers

    Journal of Therapeutic Ultrasound 2017 5:5

    Published on: 2 March 2017

  3. Research

    Objective image analysis of real-time three-dimensional intraoperative ultrasound for intrinsic brain tumour surgery

    There is growing evidence that maximal surgical resection of primary intrinsic brain tumours is beneficial, both by improving progression free and overall survival and also by facilitating postoperative chemot...

    Sophie J. Camp, Vasileios Apostolopoulos, Vasileios Raptopoulos, Amrish Mehta, Kevin O’Neill, Mohammed Awad, Babar Vaqas, David Peterson, Federico Roncaroli and Dipankar Nandi

    Journal of Therapeutic Ultrasound 2017 5:2

    Published on: 16 February 2017

  4. Research

    Moderate-to-deep sedation technique, using propofol and ketamine, allowing synchronised breathing for magnetic resonance high-intensity focused ultrasound (MR-HIFU) treatment for uterine fibroids: a pilot study

    Magnetic resonance high-intensity focused ultrasound (MR-HIFU) treatment for uterine fibroids is rapidly gaining popularity as a treatment modality. This procedure is generally uncomfortable, painful, and requ...

    Hermanus H. B. Vaessen, F. M. Knuttel, J. M. M. van Breugel, M. E. Ikink, J. M. Dieleman, M. A. A. J. van den Bosch and J. T. A. Knape

    Journal of Therapeutic Ultrasound 2017 5:8

    Published on: 9 February 2017

  5. Case study

    MRgFUS for desmoid tumors within the thigh: early clinical experiences

    Desmoid tumors are benign but locally aggressive non-malignant tumors derived from fibroblasts. Surgery, chemotherapy, and radiation therapy have been the mainstay of treatment, but recurrence is common and si...

    Matthew D. Bucknor and Viola Rieke

    Journal of Therapeutic Ultrasound 2017 5:4

    Published on: 3 February 2017

  6. Research

    Why we should care about soft tissue interfaces when applying ultrasonic diathermy: an experimental and computer simulation study

    One goal of therapeutic ultrasound is enabling heat generation in tissue. Ultrasound application protocols typically neglect these processes of absorption and backscatter/reflection at the skin/fat, fat/muscle...

    Thaís Pionório Omena, Aldo José Fontes-Pereira, Rejane Medeiros Costa, Ricardo Jorge Simões, Marco Antônio von Krüger and Wagner Coelho de Albuquerque Pereira

    Journal of Therapeutic Ultrasound 2017 5:3

    Published on: 27 January 2017

  7. Research

    An evaluation of the sonoporation potential of low-boiling point phase-change ultrasound contrast agents in vitro

    Phase-change ultrasound contrast agents (PCCAs) offer a solution to the inherent limitations associated with using microbubbles for sonoporation; they are characterized by prolonged circulation lifetimes, and ...

    Samantha M. Fix, Anthony Novell, Yeoheung Yun, Paul A. Dayton and Christopher B. Arena

    Journal of Therapeutic Ultrasound 2017 5:7

    Published on: 24 January 2017

  8. Study protocol

    Fast and high temperature hyperthermia coupled with radiotherapy as a possible new treatment for glioblastoma

    A new transcranial focused ultrasound device has been developed that can induce hyperthermia in a large tissue volume. The purpose of this work is to investigate theoretically how glioblastoma multiforme (GBM)...

    Giovanni Borasi, Alan Nahum, Margarethus M. Paulides, Gibin Powathil, Giorgio Russo, Laura Fariselli, Debora Lamia, Roberta Cirincione, Giusi Irma Forte, Cristian Borrazzo, Barbara Caccia, Elisabetta di Castro, Silvia Pozzi and Maria Carla Gilardi

    Journal of Therapeutic Ultrasound 2016 4:32

    Published on: 8 December 2016

  9. Research

    Uncertainty estimation for temperature measurement with diagnostic ultrasound

    Ultrasound therapies are promising, non-invasive applications with potential to significantly improve, e.g. cancer therapies like viro- or immunotherapy or surgical applications. However, a crucial step toward...

    Tina A. Fuhrmann, Olga Georg, Julian Haller, Klaus-V. Jenderka and Volker Wilkens

    Journal of Therapeutic Ultrasound 2016 4:28

    Published on: 1 December 2016

  10. Meeting abstracts

    5th International Symposium on Focused Ultrasound

    Menashe Zaaroor, Alon Sinai, Dorit Goldsher, Ayelet Eran, Maria Nassar, Ilana Schlesinger, Jonathon Parker, Vinod Ravikumar, Pejman Ghanouni, Sherman Stein, Casey Halpern, Vibhor Krishna, Amelia Hargrove, Punit Agrawal, Barbara Changizi, Eric Bourekas…

    Journal of Therapeutic Ultrasound 2016 4(Suppl 1):31

    Published on: 21 November 2016

    This article is part of a Supplement: Volume 4 Supplement 1

  11. Research

    T2-based temperature monitoring in bone marrow for MR-guided focused ultrasound

    Current clinical protocols for MR-guided focused ultrasound (MRgFUS) treatment of osseous lesions, including painful bone metastases and osteoid osteomas, rely on measurement of the temperature change in adjac...

    Eugene Ozhinsky, Misung Han, Matthew Bucknor, Roland Krug and Viola Rieke

    Journal of Therapeutic Ultrasound 2016 4:26

    Published on: 17 November 2016

  12. Research

    The safety and effectiveness of volumetric magnetic resonance-guided high-intensity focused ultrasound treatment of symptomatic uterine fibroids: early clinical experience in China

    Uterine fibroids are the most common benign tumor in women, and surgical intervention is still the main fibroid treatment. Patient demands have encouraged development of less-invasive methods such as high-inte...

    Rui Chen, Bilgin Keserci, Hui Bi, Xiaobing Han, Xiaoying Wang, Wenpei Bai, Yueling Wang, Xuedong Yang, Jian Yang, Juan Wei, Minna Seppälä, Antti Viitala and Qinping Liao

    Journal of Therapeutic Ultrasound 2016 4:27

    Published on: 3 November 2016

  13. Research

    Low-intensity pulsed ultrasound stimulation in different regions in the viability of myocutaneous flaps

    Low-intensity pulsed ultrasound (LIPUS) has presented good results in the healing of chronic wounds. The objective of this study was to compare the effect of LIPUS on the viability of transverse rectus abdomin...

    Fernanda Luiza de Almeida Albuquerque, Lais Mara Siqueira das Neves and Elaine Caldeira de Oliveira Guirro

    Journal of Therapeutic Ultrasound 2016 4:25

    Published on: 21 October 2016

  14. Research

    The influence of low-intensity physiotherapeutic ultrasound on the initial stage of bone healing in rats: an experimental and simulation study

    Low-intensity physiotherapeutic ultrasound has been used in physical therapy clinics; however, there remain some scientific issues regarding the bone-healing process. The objective of this study was to investi...

    Aldo José Fontes-Pereira, Marcio Amorim, Fernanda Catelani, Daniel Patterson Matusin, Paulo Rosa, Douglas Magno Guimarães, Marco Antônio von Krüger and Wagner Coelho de Albuquerque Pereira

    Journal of Therapeutic Ultrasound 2016 4:24

    Published on: 3 October 2016

  15. Research

    MR thermometry for focused ultrasound monitoring utilizing model predictive filtering and ultrasound beam modeling

    A major challenge in using magnetic resonance temperature imaging (MRTI) to monitor focused ultrasound (FUS) applications is achieving high spatio-temporal resolution over a large field of view (FOV). This is ...

    Henrik Odéen, Scott Almquist, Joshua de Bever, Douglas A. Christensen and Dennis L. Parker

    Journal of Therapeutic Ultrasound 2016 4:23

    Published on: 22 September 2016

  16. Research

    Open-source, small-animal magnetic resonance-guided focused ultrasound system

    MR-guided focused ultrasound or high-intensity focused ultrasound (MRgFUS/MRgHIFU) is a non-invasive therapeutic modality with many potential applications in areas such as cancer therapy, drug delivery, and bl...

    Megan E. Poorman, Vandiver L. Chaplin, Ken Wilkens, Mary D. Dockery, Todd D. Giorgio, William A. Grissom and Charles F. Caskey

    Journal of Therapeutic Ultrasound 2016 4:22

    Published on: 5 September 2016

    The Erratum to this article has been published in Journal of Therapeutic Ultrasound 2016 4:29

  17. Research

    Influence of therapeutic ultrasound on the biomechanical characteristics of the skin

    Skin function is dependent on its biomechanical characteristics, resistance, malleability, and elasticity. Therapeutic ultrasound may increase cutaneous malleability thus and optimize the rehabilitation proces...

    Lígia Brancalion Catapani, Adriana da Costa Gonçalves, Nathalia Morano Candeloro, Lídia Aparecida Rossi and Elaine Caldeira de Oliveira Guirro

    Journal of Therapeutic Ultrasound 2016 4:21

    Published on: 17 August 2016

  18. Case study

    Volumetric MR-guided high-intensity focused ultrasound ablation to treat uterine fibroids through the abdominal scars using scar patch: a case report

    Abdominal scars pose a challenge in magnetic resonance-guided high-intensity focused ultrasound (MR-HIFU) therapies, limiting patient selection and increasing the risk of skin burns. Especially, scars arising ...

    Ying Zhu, Bilgin Keserci, Antti Viitala, Juan Wei, Xuedong Yang and Xiaoying Wang

    Journal of Therapeutic Ultrasound 2016 4:20

    Published on: 11 August 2016

  19. Research

    Procedural sedation and analgesia for respiratory-gated MR-HIFU in the liver: a feasibility study

    Previous studies demonstrated both pre-clinically and clinically the feasibility of magnetic resonance-guided high-intensity focused ultrasound (MR-HIFU) ablations in the liver. To overcome the associated prob...

    Johanna M. M. van Breugel, Joost W. Wijlemans, Hermanus H. B. Vaessen, Martijn de Greef, Chrit T. W. Moonen, Maurice A. A. J. van den Bosch and Mario G. Ries

    Journal of Therapeutic Ultrasound 2016 4:19

    Published on: 29 July 2016

  20. Review

    Acoustic neuromodulation from a basic science prospective

    We present here biophysical models to gain deeper insights into how an acoustic stimulus might influence or modulate neuronal activity. There is clear evidence that neural activity is not only associated with ...

    Elisabetta Sassaroli and Natalia Vykhodtseva

    Journal of Therapeutic Ultrasound 2016 4:17

    Published on: 20 May 2016

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